U.S. Drug Enforcement Administration and the Guatemalan Army worked with the Guatemalan Police to destroy poppy fields in the municipalities of Tajumulco and Ixchiguan.
The street value from heroin that would have been produced from the poppies was estimated at around $434.5 million dollars.
Drug traffickers from neighboring Mexico have turned San Marcos into a center of poppy cultivation, the Guatemalan police states.
Guatemalan security forces have destroyed more than $1.3 billion worth of opium poppies in San Marcos so far this year, according to officials.